Friday, January 8, 2010

Me, Myself and I vs. What, Where, When & Why

The article below peaks my interest since I still have no other reason for my blood clot/heart attack other than being told that I had "a lot of stress and bad luck". I wonder how the doctor officially wrote that sentence!? In fact, I am hoping to get something official in writing at my next appointment. It's a horrible feeling not knowing why. I always wanted to be a journalism major - the who, what, when, why and how is the first thing I learned (I didn't get very far in that journalism endeavor!). Anyhow, in this situation, the only answer I have pertains to who. The answer is, me. 


I went through all sorts of genetic tests following my heart attack (lupus, leukemia, I can't remember them all...) yet everything came back negative. The reason I want to know isn't just a need to know based upon reaction, I want to know so I can try to prevent it from happening again. So, for now, I still mention every little thing I can think of as it comes to mind to my doctor, no matter how silly it may seem. I think I've been in the room to many times when my husband is watching the t.v. program 'House'! Probably more ridiculous is the fact that I still have a shoe box sized box with the empty bottles of the vitamin supplements/medications I was taking when I had my heart attack - as though some recall will occur and I will have the bottles with the manufacturing information that link the mysterious contents to my heart attack (again, too much 'House'). I need to begin to accept the fact that I will never know; that I have to look at people and say "stress and bad luck", and believe it myself.  Well, on with the article (below):


Genetic Link to Heart Failure

ScienceDaily (Jan. 1, 2010) — A team of researchers, at Washington University School of Medicine, St Louis, has identified a group of 12 genetic variants in the HSPB7 gene that is associated with heart failure in humans.

The research is reported in the
Journal of Clinical Investigation. The team, led by Gerald Dorn, used an approach they have recently developed that allows ultra-high-throughput targeted DNA sequencing to identify genetic variation in four genes with biological relevance to heart failure. They identified in a large group of Caucasian individuals with heart failure, 129 separate genetic variants in the four genes, including 23 that seemed to be novel.

Further analysis of 1117 Caucasian individuals with heart failure and 625 nonaffected Caucasians indicated that a block of 12 genetic variants in the HSPB7 gene was associated with heart failure. Confirmation of this association was provided by analysis of an independent group of individuals.

The authors hope to use the same approach to identify further genetic variants associated with heart failure, a disease that is influenced by multiple genetic factors.

Wednesday, January 6, 2010

Have I Mentioned That I Love Dr. Oz?



His show, The Dr. Oz Show, premiered this past fall (2009) and I am hooked! I had already read one of his books after my heart attack.  In exchange for the time I spend watching Dr. Oz, I gave up The Martha Stewart Show!  (That says a lot, I love Martha!!)  Not an episode passes that I don't learn something new and useful regarding leading a healthier lifestyle; however I haven't been consistent about applying what I take away from the show.  'The Dr. Oz. Show' has several ongoing challenges focusing on preventative medicine (also listed on the website).  As it is the beginning of a new year, it seems like the perfect time for a personal challenge...  I never think of myself as consuming a lot of sugar, but I do!  I am still overweight and with Type 1 Diabetes in my family, there is no time like the present to get a handle on my sugar consumption (ooh, hot chocolate with whipped cream and cinnamon, how I will miss you!! - but you have way too much sugar and no matter how I try to cut the sugar, I just have to break up with you).  For this reason, I'm eyeballing the Sugar Free in 28-Days Challenge.  I've accomplished this goal before, but it was hard (and I
obviously fell off the wagon)! I guess we'll see if I have what it takes to do it again, KNOWING what I am getting myself into this time around.

I'd love to receive feedback about any lifestyle or health changes being made by others!!! 




Behind the Scenes in the O.R. With Dr. Oz
Dr. Mehmet Oz Wants Americans to Get Healthy so They Won't Need Heart Surgery
By KATIE ESCHERICH
Aug. 25, 2009—

Dr. Mehmet Oz calls the operating room where he performs 300 heart surgeries each year "the temple," but says he wishes he spent a lot less time there.  Oz is on a mission to inspire Americans to get healthy so he never needs to treat them.
Oz gave Diane Sawyer a rare look inside the operating room at New York-Presbyterian Hospital/Columbia Medical Center to see just what happens during open heart surgery.

"In every case, every single operation, there is one moment where the patient could die," he said. "I don't remember ever in my whole life not having that be part of an operation. It's not that I think it's going to happen, but I realize if I go left rather than go right, we'll have a catastrophe."
For surgeons, the preparation starts before they make a single cut, when they're scrubbing in.
"The ritual starts off with the fingernails," Oz said. "I only point this out because there's a lot of superstition in surgery. The good surgeons would spend the time meditating about what they're about to do, actually going through it in their mind. So when you're in there and everyone's wondering what you're going to do next, you've already thought about it three times while you were scrubbing."
Oz, who treats patients with the highest-tech heart surgery and care, knows 70 percent of his patients could have lived differently and never had to be lying on his table. And that's why he says he doesn't favor one health care plan over another.
"The big debate right now in Washington is health care finance," he said. "It's how are you going to pay for it. I don't care which program we pick. I'll tell you why. Because none of them are going to work."
Oz says the health care plans are all doomed unless Americans create a new way of thinking about health. He says there have to be incentives for healthy behavior at the workplace, in families, with our children, with each other and points out that Americans have, on average, twice as much chronic disease than Europeans.
"What we haven't done is get to the very root reality of the flaws we have in the health care system," he said. "True health care reform cannot happen in Washington. It has to happen in our kitchens, in our homes, in our communities. All health care is personal."
And it also complicated.
"I don't think the solution is as simple as saying, 'walk 30 minutes a day,'" he said. "The solution is much more profound than me barking out orders about how much you have to exercise."
Healthy Lifestyle Key to Avoiding Heart SurgeryThe solution will come, he says, when it's easier to make the healthy choice than the unhealthy choice.  "If I make your workplace conducive to walking at lunch, or working out at some time during the day, or I get people to use the stairs more by creating incentives to do such, then people will start doing it naturally," Oz said.  "We don't walk," he continued. "We overeat because we've made it easy to overeat. We have fast-food joints on every corner. By the way, the 'we' is all of us. It's not the government. It's all of us doing this together."  Oz says that while one-third of health issues are genetic, two-thirds are the result of factors that we have the ability to alter, like walking regularly, eating plenty of leafy green vegetables and fruits, and losing weight.  In the operating room, Oz showed Sawyer a heart valve he removed from the patient. It stopped working because of calcium deposits.

Many of the patients he sees are suffering the effects of smoking.  "I don't operate on smokers," he said. "I tell cigarette smokers that I can operate on you, I get paid the same. And you might even do well. But it's the wrong thing to do. So I refuse to operate on you until you stop smoking."  He promises to do whatever he can to help patients stop smoking.
"In my entire career, I've never had a patient not stop," he said.
Unfortunately, many resume smoking after surgery despite follow-up treatment.
"I recognize that the average smoker stops and then starts again six times before they succeed," he said. "At least I took care of one of 'em."

Oz says the hardest thing for a surgeon to come to terms with is someone who's been through surgery and still hasn't responded to the message about exercise and weight.
Dr. Oz: 'Put Me Out of Business'
Peter Calafati, a 52-year-old who had a coronary bypass five months ago, still has trouble with exercise -- and some of that stomach is back.
"I look at you and I blame myself," Oz told him. "I say, I must have walked him through all the details of open heart surgery but & I didn't get into his heart and get him to appreciate why I feel so passionately about doing these things."
"It's laziness on that area, you know?" Calafati said. "It wasn't like a life-shattering moment for me, it was almost somewhat expected."
"That is actually the most cogent answer I have ever gotten to that question," Oz said, adding that coronary bypass never used to be done on patients as young as Calafati or others he treats.
"It's being done on 25-year-olds," he said.
The rise in surgical procedures may be good for business for a surgeon, but Oz is hoping for the opposite.
"The main reason that I really wanted you to come is to put me out of business," Oz said in the operating room. "Because although this is extremely fulfilling and I really do enjoy it a lot at its very foundation, you walk in there and you realize my goodness, this didn't have to happen."
Preventative medicine will be the focus of "The Dr. Oz Show," which premieres on Sept. 14, 2009.
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